Celavie Biosciences Technology
We apply our proprietary technology
across 4 mammalian lines, with all lines expressing similar stem cell markers.
Research in one area feeds the
product pipeline in another area.
Advancing Beyond Mainstream Cell Technology
A key feature of Celavie’s approach, which sets it apart from mainstream stem cell technology, is that the cells are not matured before use, as is the case with embryonic and many adult stem cells. The theoretical premise of this approach is that undifferentiated stem cells are pluripotent; as such they can read biochemical and genetic cues in the micro environment into which they are injected, in response becoming any cell type required to repair tissues that have been damaged by chronic disease, use, or trauma.
Celavie uses the latest technological breakthroughs in bioreactors to produce large banks of undifferentiated cells with uniform reproducible and stable qualities. The cells are grown in a specialized patented medium that allows them to maintain their genetic stability over the course of the manufacturing process.
Celavie and Celavet Stem Cells vs. Other Cells
Cell type | Potency | Healing potential | Tumorigenicity | Turnaround time | Percent stem cells in final formulation | Requires Cells to be PreDifferentiated |
---|---|---|---|---|---|---|
Autologous Adult Stem Cells | Multipotent |
Limited |
No |
Long |
Low |
No |
Embryonic Stem Cells | Pluripotent |
High |
YES |
Short |
High |
Yes |
Induced Pluripotent Cells | Pluripotent |
High |
YES |
Long |
Varies |
Yes |
Celavie/Celavet Stem Cells | Pluripotent |
High |
No |
Short |
High |
No |
Unique Properties of Celavie Stem Cells
Sterility and the integrity of the manufacturing process are realized through the use of the closed-system bioreactor and automated separation and dispensing systems in full compliance with Good Manufacturing Practice. The manufacturing process utilizes an industry-accepted, multi-tier cell banking system. Every bank of cells is required to meet stringent requirements for viability, genetic stability, and absence of infectious agents prior to being added to a cryobank. When required for treatment, our cells are thawed, reintroduced to the transportation medium, and shipped to the clinical location overnight.
Clinical Approaches
We believe that Celavie’s stem cells, with their restorative power and their versatility to become multiple tissues, represent humanity’s best hope for a cure for many unaddressed or underserved degenerative diseases and injuries. We have shown in vitro that our stem cells are capable of maturing into a wide range of adult stem cells that can be applied to a number of diseases:
- Dopamine Producing Neurons for Parkinson’s Disease
- Cardiomyocytes for Myocardial Infarction
- Tenocytes for Tendon Injuries
- Fibroblasts for Ligament Injuries
- Chondrocytes for Joint Injuries
- Osteoblasts for Bone Injuries
Foundational Theory
Celavie’s undifferentiated cells may:
- Migrate to the site of the disorder
- Read the microenvironment into which they are transplanted
- Multiply and differentiate according to the nature and severity of the disorder
- Repair structure and restore function